关键词: 眼睑黑色素瘤/治疗

Abstract: Eyelid malignant melanoma is a rare tumor which incidence rate is higher in white race than in other races. Aged-people is susceptible. Excessive ultraviolet exposure relates to the malignant tumor. The lower eyelid is more likely to suffer from this disease than the upper eyelid. Eyelid malignant melanoma is often manifested as changes in the size, color and shape of the previous pigmented nevus of the eyelid, or a sudden new dark brown mass. With a high degree of malignancy, the tumor can metastasize to local lymph nodes or other organs in the late stage. Early diagnosis is very important, and the diagnosis requires histopathological examination. Extensive local excision is the main treatment method of this disease. Eyelid reconstruction should be considered if the resection range is large. At present, immunotherapy, as one of the new treatment methods for eyelid malignant melanoma, has attracted more and more attention. The application of immune checkpoint inhibitors on this disease may have a broad prospect.(Int Rev Ophthalmol, 2022, 46: 420-424)

Key words: eyelid melanoma/therapy